药物动力学名词英中文对照表

发布时间: 2012-12-19 15:17   来源:
关键词: 英语
药物动力学名词英中文对照表

absorption 吸收 

albumin 白蛋白 

allometric scaling 类比法 

apparent volume of distribution 表观分布容积 

biliary excretion 胆汁排泄 

bioavailability 生物利用度 

bioequivalence 生物等效性 

biopharmaceutics 生物药剂学 

blood brain-barrier 血脑屏障 

blood-to-plasma concentration ratio 血液-血浆浓度比 

central compartment 中央室 

chiral drug 手性药物 

clearance 清除 

clearance rate 清除率 

clinical pharmacokinetics 临床药物动力学 

compartment 房室,隔室 

competitive inhibition 竞争性抑制 

conjugation 结合 

dissolution 溶解 

distribution 分布 

dosage regimen 给药方案 

drug interactions 药物之间相互作用 

elimination 消除 

elimination rate constant 消除速率常数 

enantiomer 对映体 

enteric-coated tablets 肠溶片



enterohepatic cycle 肝肠循环 

enzyme 酶 

equilibrium 平衡 

excretion 排泄 

extensive metabolizers 快代谢型 

fecal excretion 粪排泄 

first-pass effect 首过效应,首关效应 

formulation 剂型 

gastric emptying 胃排空 

genetic polymorphism 遗传多态性 

glomerular filtration rate 肾小球滤过率 

half-life 半衰期 

hepatic clearance 肝清除率 

hepatocytes 肝细胞 

high throughput screening 高通量药物筛选 

hydrolysis 水解 

in silico modeling (modelling) 计算机模拟 

in vitro 体外 

in vivo 体内 

individualized therapy 个体化给药,个体化治疗 

inducer 诱导剂 

induction 诱导 

infusion 注射 

inhibitor 抑制剂 

inhibition 抑制 

interactions (see: drug interactions) 相互作用 

intramuscular administration 肌肉注射 

intestinal transit time 肠道通过时间,经肠时间 

intravenous administration 静脉注射 

intrinsic clearance 内在清除率 

ionization 离子化 

liver microsomes 肝微粒体 

liver slices 肝切片 

mechanism-based inhibition 机理性抑制 

Michaelis constant 米氏常数 

Michaelis-Menten equation 米氏方程 

metabolism 代谢 

noncompetitive inhibition 非竞争性抑制 

oral administration 口服给药 

oxidation 氧化 

P-glycoprotein P-糖蛋白 

partition coefficint 分配系数 

passive diffusion 被动扩散 

perfusion rate 灌注速率 

peripheral compartment 外周室 

permeability 通透性系数 

pharmacodynatics 药效学 

pharmacogenetics 遗传药理学 

pharmacogenomics 药物基因组学 



pharmacokinetics 药物动力学 

physiology 生理 

placental barrier 胎盘屏障 

plasma 血浆 

plasma protein binding 血浆蛋白结合度 

polymorphism 多态性 

poor metabolizers 慢代谢型 

population pharmacokinetics, POPPK 群体药物动力学 

racemate 外消旋体 

recombinant enzymes 重组酶 

reduction 还原 

renal clearance 肾清除率 

renal function 肾功能 

sampling 样品,样本 

scaling factor 比放系数 

solubility 溶解度 

steady state 稳态 

substrate 底物 

toxicology 毒理学 

transporter 载体 

uncompetitive inhibition 反竞争性抑制 

variability (inter-individual variability) 个体差异 

virtual screening 虚拟筛选 

volume of distribution 分布容积 

xenobiotics 外源物 

药物动力学相关的生理学名词 

adipose 脂肪 

bile 胆汁 

cecum 盲肠 

colon 结肠 

duodenum 十二指肠 

gallbladder 胆囊 

gastrointestinal tract 胃肠道 

ileum 回肠 

jejunum 空肠 

large intestine 大肠 

liver 肝 

pancreas 胰腺 

rectum 直肠 

small intestine 小肠 

spleen 脾 

stomach 胃 

urine 尿液



  


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